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Spontaneous Switching among Conformational Ensembles in Intrinsically Disordered Proteins

The common conception of intrinsically disordered proteins (IDPs) is that they stochastically sample all possible configurations driven by thermal fluctuations. This is certainly true for many IDPs, which behave as swollen random coils that can be described using polymer models developed for homopol...

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Detalles Bibliográficos
Publicado en:Biomolecules
Main Authors: Choi, Ucheor B., Sanabria, Hugo, Smirnova, Tatyana, Bowen, Mark E., Weninger, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468417/
https://ncbi.nlm.nih.gov/pubmed/30909517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9030114
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