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Spontaneous Switching among Conformational Ensembles in Intrinsically Disordered Proteins

The common conception of intrinsically disordered proteins (IDPs) is that they stochastically sample all possible configurations driven by thermal fluctuations. This is certainly true for many IDPs, which behave as swollen random coils that can be described using polymer models developed for homopol...

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Bibliografiske detaljer
Udgivet i:Biomolecules
Main Authors: Choi, Ucheor B., Sanabria, Hugo, Smirnova, Tatyana, Bowen, Mark E., Weninger, Keith R.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468417/
https://ncbi.nlm.nih.gov/pubmed/30909517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9030114
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