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Stereocontrolled Synthesis of 1,4‐Dicarbonyl Compounds by Photochemical Organocatalytic Acyl Radical Addition to Enals

We report a visible‐light‐mediated organocatalytic strategy for the enantioselective acyl radical conjugate addition to enals, leading to valuable 1,4‐dicarbonyl compounds. The process capitalizes upon the excited‐state reactivity of 4‐acyl‐1,4‐dihydropyridines that, upon visible‐light absorption, c...

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Publicado en:Angew Chem Int Ed Engl
Autores principales: Goti, Giulio, Bieszczad, Bartosz, Vega‐Peñaloza, Alberto, Melchiorre, Paolo
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468318/
https://ncbi.nlm.nih.gov/pubmed/30419156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201810798
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