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Light‐Driven Enantioselective Organocatalytic β‐Benzylation of Enals

A photochemical organocatalytic strategy for the direct enantioselective β‐benzylation of α,β‐unsaturated aldehydes is reported. The chemistry capitalizes upon the light‐triggered enolization of 2‐alkyl‐benzophenones to afford hydroxy‐o‐quinodinomethanes. These fleeting intermediates are stereoselec...

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Bibliografiska uppgifter
I publikationen:Angew Chem Int Ed Engl
Huvudupphovsmän: Dell'Amico, Luca, Fernández‐Alvarez, Victor M., Maseras, Feliu, Melchiorre, Paolo
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412672/
https://ncbi.nlm.nih.gov/pubmed/28185401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201612159
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