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Stereocontrolled Synthesis of 1,4‐Dicarbonyl Compounds by Photochemical Organocatalytic Acyl Radical Addition to Enals

We report a visible‐light‐mediated organocatalytic strategy for the enantioselective acyl radical conjugate addition to enals, leading to valuable 1,4‐dicarbonyl compounds. The process capitalizes upon the excited‐state reactivity of 4‐acyl‐1,4‐dihydropyridines that, upon visible‐light absorption, c...

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Dades bibliogràfiques
Publicat a:Angew Chem Int Ed Engl
Autors principals: Goti, Giulio, Bieszczad, Bartosz, Vega‐Peñaloza, Alberto, Melchiorre, Paolo
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468318/
https://ncbi.nlm.nih.gov/pubmed/30419156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201810798
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