From identification to functional characterization of cyriotoxin‐1a, an antinociceptive toxin from the spider Cyriopagopus schioedtei

BACKGROUND AND PURPOSE: The Na(V)1.7 channel is highly expressed in dorsal root ganglia of the sensory nervous system and plays a central role in the pain signalling process. We investigated a library prepared from original venoms of 117 different animals to identify new selective inhibitors of this...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Br J Pharmacol
Main Authors: Gonçalves, Tânia C., Benoit, Evelyne, Kurz, Michael, Lucarain, Laetitia, Fouconnier, Sophie, Combemale, Stéphanie, Jaquillard, Lucie, Schombert, Brigitte, Chambard, Jean‐Marie, Boukaiba, Rachid, Hessler, Gerhard, Bohme, Andrees, Bialy, Laurent, Hourcade, Stéphane, Béroud, Rémy, De Waard, Michel, Servent, Denis, Partiseti, Michel
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Research Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468265/
https://ncbi.nlm.nih.gov/pubmed/30784059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14628
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