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Electrophysiological and Pharmacological Characterization of Human Inwardly Rectifying K(ir)2.1 Channels on an Automated Patch-Clamp Platform
Inwardly rectifying I(K1) potassium currents of the heart control the resting membrane potential of ventricular cardiomyocytes during diastole and contribute to their repolarization after each action potential. Mutations in the gene encoding K(ir)2.1 channels, which primarily conduct ventricular I(K...
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| Publicado no: | Assay Drug Dev Technol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc., publishers
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6479253/ https://ncbi.nlm.nih.gov/pubmed/30835490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2018.882 |
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