Development and Validation of Fluorescence-Based and Automated Patch Clamp–Based Functional Assays for the Inward Rectifier Potassium Channel Kir4.1

The inward rectifier potassium (Kir) channel Kir4.1 plays essential roles in modulation of neurotransmission and renal sodium transport and may represent a novel drug target for temporal lobe epilepsy and hypertension. The molecular pharmacology of Kir4.1 is limited to neurological drugs, such as fl...

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Main Authors: Raphemot, Rene, Kadakia, Rishin J., Olsen, Michelle L., Banerjee, Sreedatta, Days, Emily, Smith, Stephen S., Weaver, C. David, Denton, Jerod S.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2013
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Original ArticlesIon Channel Focus
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870600/
https://ncbi.nlm.nih.gov/pubmed/24266659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2013.544
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