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Automated whole-cell patch clamp electrophysiology of neurons in vivo

Whole-cell patch clamp electrophysiology of neurons is a gold standard technique for high-fidelity analysis of the biophysical mechanisms of neural computation and pathology but it requires great skill to perform. We have developed a robot that automatically performs patch clamping in vivo, algorith...

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Bibliographic Details
Main Authors: Kodandaramaiah, Suhasa B., Franzesi, Giovanni Talei, Chow, Brian Y., Boyden, Edward S., Forest, Craig R.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427788/
https://ncbi.nlm.nih.gov/pubmed/22561988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1993
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