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Electrophysiological and Pharmacological Characterization of Human Inwardly Rectifying K(ir)2.1 Channels on an Automated Patch-Clamp Platform

Inwardly rectifying I(K1) potassium currents of the heart control the resting membrane potential of ventricular cardiomyocytes during diastole and contribute to their repolarization after each action potential. Mutations in the gene encoding K(ir)2.1 channels, which primarily conduct ventricular I(K...

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Bibliografische gegevens
Gepubliceerd in:Assay Drug Dev Technol
Hoofdauteurs: Sanson, Camille, Schombert, Brigitte, Filoche-Rommé, Bruno, Partiseti, Michel, Bohme, G. Andrees
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc., publishers 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479253/
https://ncbi.nlm.nih.gov/pubmed/30835490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2018.882
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