From identification to functional characterization of cyriotoxin‐1a, an antinociceptive toxin from the spider Cyriopagopus schioedtei

BACKGROUND AND PURPOSE: The Na(V)1.7 channel is highly expressed in dorsal root ganglia of the sensory nervous system and plays a central role in the pain signalling process. We investigated a library prepared from original venoms of 117 different animals to identify new selective inhibitors of this...

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Detaylı Bibliyografya
Yayımlandı:Br J Pharmacol
Asıl Yazarlar: Gonçalves, Tânia C., Benoit, Evelyne, Kurz, Michael, Lucarain, Laetitia, Fouconnier, Sophie, Combemale, Stéphanie, Jaquillard, Lucie, Schombert, Brigitte, Chambard, Jean‐Marie, Boukaiba, Rachid, Hessler, Gerhard, Bohme, Andrees, Bialy, Laurent, Hourcade, Stéphane, Béroud, Rémy, De Waard, Michel, Servent, Denis, Partiseti, Michel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468265/
https://ncbi.nlm.nih.gov/pubmed/30784059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14628
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