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A high-throughput screen identifies small molecule modulators of alternative splicing by targeting RNA G-quadruplexes
RNA secondary structures have been increasingly recognized to play an important regulatory role in post-transcriptional gene regulation. We recently showed that RNA G-quadruplexes, which serve as cis-elements to recruit splicing factors, play a critical role in regulating alternative splicing during...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6468248/ https://ncbi.nlm.nih.gov/pubmed/30698802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz036 |
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