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RNA G-quadruplex secondary structure promotes alternative splicing via the RNA-binding protein hnRNPF

It is generally thought that splicing factors regulate alternative splicing through binding to RNA consensus sequences. In addition to these linear motifs, RNA secondary structure is emerging as an important layer in splicing regulation. Here we demonstrate that RNA elements with G-quadruplex-formin...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Huang, Huilin, Zhang, Jing, Harvey, Samuel E., Hu, Xiaohui, Cheng, Chonghui
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769772/
https://ncbi.nlm.nih.gov/pubmed/29269483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.305862.117
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