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RNA G-quadruplex secondary structure promotes alternative splicing via the RNA-binding protein hnRNPF

It is generally thought that splicing factors regulate alternative splicing through binding to RNA consensus sequences. In addition to these linear motifs, RNA secondary structure is emerging as an important layer in splicing regulation. Here we demonstrate that RNA elements with G-quadruplex-formin...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Huang, Huilin, Zhang, Jing, Harvey, Samuel E., Hu, Xiaohui, Cheng, Chonghui
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769772/
https://ncbi.nlm.nih.gov/pubmed/29269483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.305862.117
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