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A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators
Alternative splicing has emerged as a promising therapeutic target in a number of human disorders. However, the discovery of compounds that target the splicing reaction has been hindered by the lack of suitable high-throughput screening assays. Conversely, the effects of known drugs on the splicing...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516208/ https://ncbi.nlm.nih.gov/pubmed/18678901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801661105 |
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