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Click-Mediated Pretargeted Radioimmunotherapy of Colorectal Carcinoma

Pretargeted radioimmunotherapy (PRIT) based on the inverse electron demand Diels-Alder (IEDDA) reaction between tetrazine (Tz) and trans-cyclooctene (TCO) represents a promising strategy for leveraging the affinity and specificity of antibodies without their pharmacokinetic drawbacks. Herein, we pre...

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Bibliografische gegevens
Gepubliceerd in:Mol Pharm
Hoofdauteurs: Membreno, Rosemery, Cook, Brendon E., Fung, Kimberly, Lewis, Jason S., Zeglis, Brian M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467224/
https://ncbi.nlm.nih.gov/pubmed/29502416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b00093
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