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A Dendrimer Scaffold for the Amplification of In Vivo Pretargeting Ligations

The development of immunoconjugates requires a careful balance between preserving the functionality of the antibody and modifying the immunoglobulin with the desired cargo. Herein, we describe the synthesis, development, in vivo evaluation of a novel bifunctional dendrimeric scaffold and its applica...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioconjug Chem
Prif Awduron: Cook, Brendon E., Membreno, Rosemery, Zeglis, Brian M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432625/
https://ncbi.nlm.nih.gov/pubmed/29969558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.8b00385
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