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A Dendrimer Scaffold for the Amplification of In Vivo Pretargeting Ligations

The development of immunoconjugates requires a careful balance between preserving the functionality of the antibody and modifying the immunoglobulin with the desired cargo. Herein, we describe the synthesis, development, in vivo evaluation of a novel bifunctional dendrimeric scaffold and its applica...

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Bibliografiske detaljer
Udgivet i:Bioconjug Chem
Main Authors: Cook, Brendon E., Membreno, Rosemery, Zeglis, Brian M.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432625/
https://ncbi.nlm.nih.gov/pubmed/29969558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.8b00385
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