Comparative Study of Chemical Stability of Two H(1) Antihistaminic Drugs, Terfenadine and Its In Vivo Metabolite Fexofenadine, Using LC-UV Methods

A comparative study of chemical stability of terfenadine (TER) and its in vivo metabolite fexofenadine (FEX) was performed. Both TER and FEX were subjected to high temperature at different pH and UV/VIS light at different pH and then quantitatively analyzed using new validated LC-UV methods. These m...

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Publicado en:J Anal Methods Chem
Autores principales: Gumieniczek, Anna, Berecka-Rycerz, Anna, Pietraś, Rafał, Kozak, Izabela, Lejwoda, Karolina, Kozyra, Paweł
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466962/
https://ncbi.nlm.nih.gov/pubmed/31061743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5790404
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