Comparative Study of Chemical Stability of Two H(1) Antihistaminic Drugs, Terfenadine and Its In Vivo Metabolite Fexofenadine, Using LC-UV Methods

A comparative study of chemical stability of terfenadine (TER) and its in vivo metabolite fexofenadine (FEX) was performed. Both TER and FEX were subjected to high temperature at different pH and UV/VIS light at different pH and then quantitatively analyzed using new validated LC-UV methods. These m...

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Gepubliceerd in:J Anal Methods Chem
Hoofdauteurs: Gumieniczek, Anna, Berecka-Rycerz, Anna, Pietraś, Rafał, Kozak, Izabela, Lejwoda, Karolina, Kozyra, Paweł
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466962/
https://ncbi.nlm.nih.gov/pubmed/31061743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5790404
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