Comparative Study of Chemical Stability of Two H(1) Antihistaminic Drugs, Terfenadine and Its In Vivo Metabolite Fexofenadine, Using LC-UV Methods

A comparative study of chemical stability of terfenadine (TER) and its in vivo metabolite fexofenadine (FEX) was performed. Both TER and FEX were subjected to high temperature at different pH and UV/VIS light at different pH and then quantitatively analyzed using new validated LC-UV methods. These m...

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Publicat a:J Anal Methods Chem
Autors principals: Gumieniczek, Anna, Berecka-Rycerz, Anna, Pietraś, Rafał, Kozak, Izabela, Lejwoda, Karolina, Kozyra, Paweł
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466962/
https://ncbi.nlm.nih.gov/pubmed/31061743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5790404
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