Poly(ethylene glycol)-block-poly(D,L-lactic acid) Micelles containing Oligo(lactic acid)(8)-Paclitaxel Prodrug: In Vivo Conversion and Antitumor Efficacy

Poly(ethylene glycol)-block-poly(D,L-lactic acid) (PEG-b-PLA) micelles affect drug solubilization, and a paclitaxel (PTX) loaded-PEG-b-PLA micelle (PTX-PM) is approved for cancer treatment due to injection safety and dose escalation (Genexol-PM®) compares to Taxol®. However, PTX-PM is unstable in bl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Control Release
Egile Nagusiak: Tam, Yu Tong, Shin, Dae Hwan, Chen, Karen E., Kwon, Glen S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466635/
https://ncbi.nlm.nih.gov/pubmed/30790593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.02.017
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