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Pharmacokinetic study of 3-in-1 poly(ethylene glycol)-block-poly(D, L-lactic acid) micelles carrying paclitaxel, 17-allylamino-17-demethoxygeldanamycin, and rapamycin

Concurrent delivery of multiple poorly water-soluble anticancer drugs has been a great challenge due to the toxicities exerted by different surfactants or organic solvents used in solubilizing individual drugs. We previously found that poly(ethylene glycol)-block-poly(D, L-lactic acid) (PEG-b-PLA) m...

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Autori principali: Shin, Ho-Chul, Cho, Hyunah, Lai, Tsz Chung, Kozak, Kevin R., Kolesar, Jill M., Kwon, Glen S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422612/
https://ncbi.nlm.nih.gov/pubmed/22549011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.04.024
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