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Homozygous Recessive MYH2 Mutation Mimicking Dominant MYH2 Associated Myopathy

Mutations in MYH2 that encodes myosin heavy chain IIa cause both dominant and recessively inherited myopathies. Patients with dominantly inherited MYH2 missense mutations present with ophthalmoplegia and progressive proximal limb weakness. Muscle biopsy reveals rimmed vacuoles and inclusions, prompt...

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Bibliographic Details
Published in:Neuromuscul Disord
Main Authors: Findlay, Andrew R., Harms, Matthew B., Pestronk, Alan, Weihl, Conrad C.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466613/
https://ncbi.nlm.nih.gov/pubmed/29934118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nmd.2018.05.006
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