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Homozygous Recessive MYH2 Mutation Mimicking Dominant MYH2 Associated Myopathy

Mutations in MYH2 that encodes myosin heavy chain IIa cause both dominant and recessively inherited myopathies. Patients with dominantly inherited MYH2 missense mutations present with ophthalmoplegia and progressive proximal limb weakness. Muscle biopsy reveals rimmed vacuoles and inclusions, prompt...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuromuscul Disord
Prif Awduron: Findlay, Andrew R., Harms, Matthew B., Pestronk, Alan, Weihl, Conrad C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466613/
https://ncbi.nlm.nih.gov/pubmed/29934118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nmd.2018.05.006
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