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Valosin-containing protein disease: inclusion body myopathy with Paget's disease of the bone and fronto-temporal dementia

Mutations in valosin-containing protein (VCP) cause inclusion body myopathy (IBM) associated with Paget's disease of the bone (PDB) and fronto-temporal dementia (FTD) or IBMPFD. Although IBMPFD is a multisystem disorder, muscle weakness is the presenting symptom in greater than half of patients...

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Detalhes bibliográficos
Main Authors: Weihl, Conrad C., Pestronk, Alan, Kimonis, Virginia E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859037/
https://ncbi.nlm.nih.gov/pubmed/19380227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nmd.2009.01.009
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