Drug Design and Synthesis of First in Class PDZ1 Targeting NHERF1 Inhibitors as Anticancer Agents

[Image: see text] Targeted approaches aiming at modulating NHERF1 activity, rather than its overall expression, would be preferred to preserve the normal functions of this versatile protein. We focused our attention on the NHERF1/PDZ1 domain that governs its membrane recruitment/displacement through...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:ACS Med Chem Lett
मुख्य लेखकों: Coluccia, Antonio, La Regina, Giuseppe, Naccarato, Valentina, Nalli, Marianna, Orlando, Viviana, Biagioni, Stefano, De Angelis, Maria Laura, Baiocchi, Marta, Gautier, Candice, Gianni, Stefano, Di Pastena, Fiorella, Di Magno, Laura, Canettieri, Gianluca, Coluccia, Addolorata Maria Luce, Silvestri, Romano
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Chemical Society 2019
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466550/
https://ncbi.nlm.nih.gov/pubmed/30996786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00532
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन