Loading...
Mutation-specific peripheral and ER quality control of hERG channel cell-surface expression
Impaired functional plasma membrane (PM) expression of the hERG K(+)-channel is associated with Long-QT syndrome type-2 (LQT2) and increased risk of cardiac arrhythmia. Reduced PM-expression is primarily attributed to retention and degradation of misfolded channels by endoplasmic reticulum (ER) prot...
Na minha lista:
| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6465299/ https://ncbi.nlm.nih.gov/pubmed/30988392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42331-6 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|