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Ubiquitination-dependent quality control of hERG K(+) channel with acquired and inherited conformational defect at the plasma membrane
Membrane trafficking in concert with the peripheral quality control machinery plays a critical role in preserving plasma membrane (PM) protein homeostasis. Unfortunately, the peripheral quality control may also dispose of partially or transiently unfolded polypeptides and thereby contribute to the l...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Cell Biology
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3861077/ https://ncbi.nlm.nih.gov/pubmed/24152733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-07-0417 |
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