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Antidepressant-induced Ubiquitination and Degradation of the Cardiac Potassium Channel hERG
The most common cause for adverse cardiac events by antidepressants is acquired long QT syndrome (acLQTS), which produces electrocardiographic abnormalities that have been associated with syncope, torsade de pointes arrhythmias, and sudden cardiac death. acLQTS is often caused by direct block of the...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Biochemistry and Molecular Biology
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190784/ https://ncbi.nlm.nih.gov/pubmed/21832094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254367 |
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