Laddar...

Molecular Determinants of Pentamidine-Induced hERG Trafficking Inhibition

Pentamidine is an antiprotozoal compound that clinically causes acquired long QT syndrome (acLQTS), which is associated with prolonged QT intervals, tachycardias, and sudden cardiac arrest. Pentamidine delays terminal repolarization in human heart by acutely blocking cardiac inward rectifier current...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Dennis, Adrienne T., Wang, Lu, Wan, Hanlin, Nassal, Drew, Deschenes, Isabelle, Ficker, Eckhard
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Pharmacology and Experimental Therapeutics 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263949/
https://ncbi.nlm.nih.gov/pubmed/22046004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.075135
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!