Nalaganje...
Molecular Determinants of hERG Channel Block by Terfenadine and Cisapride
Block of cardiac hERG K(+) channels by the antihistamine terfenadine and the prokinetic agent cisapride is associated with prolonged ventricular repolarization and an increased risk of ventricular arrhythmia. Here, we used a site-directed mutagenesis approach to determine the molecular determinants...
Shranjeno v:
| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2845965/ https://ncbi.nlm.nih.gov/pubmed/18987434 |
| Oznake: |
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