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A network of human functional gene interactions from knockout fitness screens in cancer cells

Genetic interactions mediate the emergence of phenotype from genotype. The systematic survey of genetic interactions in yeast showed that genes operating in the same biological process have highly correlated genetic interaction profiles, and this observation has been exploited to infer gene function...

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Bibliografiske detaljer
Udgivet i:Life Sci Alliance
Main Authors: Kim, Eiru, Dede, Merve, Lenoir, Walter F, Wang, Gang, Srinivasan, Sanjana, Colic, Medina, Hart, Traver
Format: Artigo
Sprog:Inglês
Udgivet: Life Science Alliance LLC 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464042/
https://ncbi.nlm.nih.gov/pubmed/30979825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800278
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