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A network of human functional gene interactions from knockout fitness screens in cancer cells

Genetic interactions mediate the emergence of phenotype from genotype. The systematic survey of genetic interactions in yeast showed that genes operating in the same biological process have highly correlated genetic interaction profiles, and this observation has been exploited to infer gene function...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Life Sci Alliance
Päätekijät: Kim, Eiru, Dede, Merve, Lenoir, Walter F, Wang, Gang, Srinivasan, Sanjana, Colic, Medina, Hart, Traver
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Life Science Alliance LLC 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464042/
https://ncbi.nlm.nih.gov/pubmed/30979825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800278
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