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PICKLES: the database of pooled in-vitro CRISPR knockout library essentiality screens

The adaptation of CRISPR/Cas9 systems for pooled library genetic knockout screens in mammalian cells has substantially advanced the state of the art in human functional genomics. Screening panels of cell lines for genes whose knockout imposes a significant fitness defect has dramatically expanded ou...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Lenoir, Walter F, Lim, Tassica L, Hart, Traver
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753353/
https://ncbi.nlm.nih.gov/pubmed/29077937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx993
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