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PICKLES: the database of pooled in-vitro CRISPR knockout library essentiality screens

The adaptation of CRISPR/Cas9 systems for pooled library genetic knockout screens in mammalian cells has substantially advanced the state of the art in human functional genomics. Screening panels of cell lines for genes whose knockout imposes a significant fitness defect has dramatically expanded ou...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Lenoir, Walter F, Lim, Tassica L, Hart, Traver
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753353/
https://ncbi.nlm.nih.gov/pubmed/29077937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx993
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