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BAGEL: a computational framework for identifying essential genes from pooled library screens
BACKGROUND: The adaptation of the CRISPR-Cas9 system to pooled library gene knockout screens in mammalian cells represents a major technological leap over RNA interference, the prior state of the art. New methods for analyzing the data and evaluating results are needed. RESULTS: We offer BAGEL (Baye...
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| Опубликовано в: : | BMC Bioinformatics |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833918/ https://ncbi.nlm.nih.gov/pubmed/27083490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1015-8 |
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