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A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation
Oxidative phosphorylation (OXPHOS) is the major pathway for ATP production in humans. Deficiencies in OXPHOS can arise from mutations in either mitochondrial or nuclear genomes and comprise the largest collection of inborn errors of metabolism. At present we lack a complete catalog of human genes an...
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| Publicado no: | Cell Metab |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5474757/ https://ncbi.nlm.nih.gov/pubmed/27667664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.08.017 |
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