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Genome-wide CRISPR/Cas9 Screen Identifies Host Factors Essential for Influenza Virus Replication

The emergence of influenza A viruses (IAVs) from zoonotic reservoirs poses a great threat to human health. As seasonal vaccines are ineffective against zoonotic strains, and newly transmitted viruses can quickly acquire drug resistance, there remains a need for host-directed therapeutics against IAV...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Han, Julianna, Perez, Jasmine T., Chen, Cindy, Li, Yan, Benitez, Asiel, Kandasamy, Matheswaran, Lee, Yoontae, Andrade, Jorge, tenOever, Benjamin, Manicassamy, Balaji
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939577/
https://ncbi.nlm.nih.gov/pubmed/29642015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.03.045
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