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Identifying chemogenetic interactions from CRISPR screens with drugZ
BACKGROUND: Chemogenetic profiling enables the identification of gene mutations that enhance or suppress the activity of chemical compounds. This knowledge provides insights into drug mechanism of action, genetic vulnerabilities, and resistance mechanisms, all of which may help stratify patient popu...
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| 出版年: | Genome Med |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6706933/ https://ncbi.nlm.nih.gov/pubmed/31439014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0665-3 |
| タグ: |
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