Genetic Modification of Adeno-Associated Viral Vector Type 2 Capsid Enhances Gene Transfer Efficiency in Polarized Human Airway Epithelial Cells

Cystic fibrosis (CF) is a common genetic disease characterized by defects in the expression of the CF transmembrane conductance regulator (CFTR) gene. Gene therapy offers better hope for the treatment of CF. Adeno-associated viral (AAV) vectors are capable of stable expression with low immunogenicit...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: White, April F., Mazur, Marina, Sorscher, Eric J., Zinn, Kurt R., Ponnazhagan, Selvarangan
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2008
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463989/
https://ncbi.nlm.nih.gov/pubmed/18778196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.117
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