Radioiodinated Capsids Facilitate In Vivo Non-Invasive Tracking of Adeno-Associated Gene Transfer Vectors

Viral vector mediated gene therapy has become commonplace in clinical trials for a wide range of inherited disorders. Successful gene transfer depends on a number of factors, of which tissue tropism is among the most important. To date, definitive mapping of the spatial and temporal distribution of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kothari, P., De, B. P., He, B., Chen, A., Chiuchiolo, M. J., Kim, D., Nikolopoulou, A., Amor-Coarasa, A., Dyke, J. P., Voss, H. U., Kaminsky, S. M., Foley, C. P., Vallabhajosula, S., Hu, B., DiMagno, S. G., Sondhi, D., Crystal, R. G., Babich, J. W., Ballon, D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216390/
https://ncbi.nlm.nih.gov/pubmed/28059103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39594
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