Adenovirus Capsid-Based Anti-Cocaine Vaccine Prevents Cocaine from Binding to the Nonhuman Primate CNS Dopamine Transporter

Cocaine addiction is a major problem for which there is no approved pharmacotherapy. We have developed a vaccine to cocaine (dAd5GNE), based on the cocaine analog GNE linked to the capsid proteins of a serotype 5 adenovirus, designed to evoke anti-cocaine antibodies that sequester cocaine in the blo...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Maoz, Anat, Hicks, Martin J, Vallabhjosula, Shankar, Synan, Michael, Kothari, Paresh J, Dyke, Jonathan P, Ballon, Douglas J, Kaminsky, Stephen M, De, Bishnu P, Rosenberg, Jonathan B, Martinez, Diana, Koob, George F, Janda, Kim D, Crystal, Ronald G
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773666/
https://ncbi.nlm.nih.gov/pubmed/23660705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.114
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires