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Human DNA polymerase η has reverse transcriptase activity in cellular environments

Classical DNA and RNA polymerase (pol) enzymes have defined roles with their respective substrates, but several pols have been found to have multiple functions. We reported previously that purified human DNA pol η (hpol η) can incorporate both deoxyribonucleoside triphosphates (dNTPs) and ribonucleo...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Su, Yan, Ghodke, Pratibha P., Egli, Martin, Li, Lin, Wang, Yinsheng, Guengerich, F. Peter
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463694/
https://ncbi.nlm.nih.gov/pubmed/30842261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007925
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