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Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase η

Ribonucleotides and 2′-deoxyribonucleotides are the basic units for RNA and DNA, respectively, and the only difference is the extra 2′-OH group on the ribonucleotide sugar. Cellular rNTP concentrations are much higher than those of dNTP. When copying DNA, DNA polymerases not only select the base of...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Su, Yan, Egli, Martin, Guengerich, F. Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759156/
https://ncbi.nlm.nih.gov/pubmed/26740629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.706226
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