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Human DNA polymerase η has reverse transcriptase activity in cellular environments

Classical DNA and RNA polymerase (pol) enzymes have defined roles with their respective substrates, but several pols have been found to have multiple functions. We reported previously that purified human DNA pol η (hpol η) can incorporate both deoxyribonucleoside triphosphates (dNTPs) and ribonucleo...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Su, Yan, Ghodke, Pratibha P., Egli, Martin, Li, Lin, Wang, Yinsheng, Guengerich, F. Peter
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463694/
https://ncbi.nlm.nih.gov/pubmed/30842261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007925
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