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Human DNA polymerase η accommodates RNA for strand extension

Ribonucleotides are the natural analogs of deoxyribonucleotides, which can be misinserted by DNA polymerases, leading to the most abundant DNA lesions in genomes. During replication, DNA polymerases tolerate patches of ribonucleotides on the parental strands to different extents. The majority of hum...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Su, Yan, Egli, Martin, Guengerich, F. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672030/
https://ncbi.nlm.nih.gov/pubmed/28972162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.809723
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