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The differential actions of clozapine and other antipsychotic drugs on the translocation of dopamine D2 receptors to the cell surface
Most clinically available antipsychotic drugs (APDs) bind dopamine D2 receptors (D2R) at therapeutic concentrations, and it is thought that they suppress psychotic symptoms by serving as competitive antagonists of dopamine at D2R. Here, we present data that demonstrate that APDs act independently of...
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| Published in: | J Biol Chem |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462534/ https://ncbi.nlm.nih.gov/pubmed/30670597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004682 |
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