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Arrestin–dependent but G–protein coupled receptor kinase–independent uncoupling of D2–dopamine receptors

We reconstituted D2 like dopamine receptor (D2R) and the delta opioid receptor (DOR) coupling to G-protein gated inwardly rectifying potassium channels (K(ir)3) and directly compared the effects of co-expression of G-protein coupled receptor kinase (GRK) and arrestin on agonist-dependent desensitiza...

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Bibliografske podrobnosti
izdano v:J Neurochem
Main Authors: Celver, Jeremy, Sharma, Meenakshi, Thanawala, Vaidehi, Octeau, J. Christopher, Kovoor, Abraham
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825321/
https://ncbi.nlm.nih.gov/pubmed/23815307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12359
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