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Metabolic and oncogenic adaptations to pyruvate dehydrogenase inactivation in fibroblasts

Eukaryotic cell metabolism consists of processes that generate available energy, such as glycolysis, the tricarboxylic acid (TCA) cycle, and oxidative phosphorylation (Oxphos), and those that consume it, including macromolecular synthesis, the maintenance of ionic gradients, and cellular detoxificat...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Wang, Huabo, Lu, Jie, Kulkarni, Sucheta, Zhang, Weiqi, Gorka, Joanna E., Mandel, Jordan A., Goetzman, Eric S., Prochownik, Edward V.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462518/
https://ncbi.nlm.nih.gov/pubmed/30755479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005200
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