Sequential adaptive changes in a c-Myc-driven model of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a common cancer that frequently overexpresses the c-Myc (Myc) oncoprotein. Using a mouse model of Myc-induced HCC, we studied the metabolic, biochemical, and molecular changes accompanying HCC progression, regression, and recurrence. These involved altered rates of...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Dolezal, James M., Wang, Huabo, Kulkarni, Sucheta, Jackson, Laura, Lu, Jie, Ranganathan, Sarangarajan, Goetzman, Eric S., Bharathi, Sivakama S., Beezhold, Kevin, Byersdorfer, Craig A., Prochownik, Edward V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473214/
https://ncbi.nlm.nih.gov/pubmed/28432125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.782052
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