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Direct observation of individual tubulin dimers binding to growing microtubules

The biochemical basis of microtubule growth has remained elusive for over 30 years despite being fundamental for both cell division and associated chemotherapy strategies. Here, we combine interferometric scattering microscopy with recombinant tubulin to monitor individual tubulins binding to and di...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Mickolajczyk, Keith J., Geyer, Elisabeth A., Kim, Tae, Rice, Luke M., Hancock, William O.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462098/
https://ncbi.nlm.nih.gov/pubmed/30804205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815823116
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